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Effects of Aneuploidy on Genome Structure, Expression, and Interphase Organization in Arabidopsis thaliana

Aneuploidy refers to losses and/or gains of individual chromosomes from the normal chromosome set. The resulting gene dosage imbalance has a noticeable affect on the phenotype, as illustrated by aneuploid syndromes, including Down syndrome in humans, and by human solid tumor cells, which are highly...

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Detalles Bibliográficos
Autores principales: Huettel, Bruno, Kreil, David P., Matzke, Marjori, Matzke, Antonius J. M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562519/
https://www.ncbi.nlm.nih.gov/pubmed/18927630
http://dx.doi.org/10.1371/journal.pgen.1000226