Cargando…
Triple-helix structure in telomerase RNA contributes to catalysis
Telomerase is responsible for replication of the ends of linear chromosomes in most eukaryotes. Its intrinsic RNA subunit provides the template for synthesis of telomeric DNA by the reverse-transcriptase (TERT) subunit and tethers other proteins into the ribonucleoprotein (RNP) complex. We report th...
Autores principales: | Qiao, Feng, Cech, Thomas R |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562722/ https://www.ncbi.nlm.nih.gov/pubmed/18500353 http://dx.doi.org/10.1038/nsmb.1420 |
Ejemplares similares
-
Structure of the Tetrahymena thermophila telomerase RNA helix II template boundary element
por: Richards, Rebecca J., et al.
Publicado: (2006) -
Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects
por: Shukla, Siddharth, et al.
Publicado: (2016) -
Single-molecule FRET-Rosetta reveals RNA structural rearrangements during human telomerase catalysis
por: Parks, Joseph W., et al.
Publicado: (2017) -
Dissecting telomerase RNA structural heterogeneity in living human cells with DMS-MaPseq
por: Forino, Nicholas M., et al.
Publicado: (2023) -
The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis
por: Berman, Andrea J., et al.
Publicado: (2011)