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A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction

Feline immunodeficiency virus (FIV) targets helper T cells by attachment of the envelope glycoprotein (Env) to CD134, a subsequent interaction with CXCR4 then facilitating the process of viral entry. As the CXCR4 binding site is not exposed until CD134-binding has occurred then the virus is protecte...

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Detalles Bibliográficos
Autores principales: Willett, Brian J, McMonagle, Elizabeth L, Logan, Nicola, Samman, Ayman, Hosie, Margaret J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563026/
https://www.ncbi.nlm.nih.gov/pubmed/18721458
http://dx.doi.org/10.1186/1742-4690-5-77