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A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction
Feline immunodeficiency virus (FIV) targets helper T cells by attachment of the envelope glycoprotein (Env) to CD134, a subsequent interaction with CXCR4 then facilitating the process of viral entry. As the CXCR4 binding site is not exposed until CD134-binding has occurred then the virus is protecte...
Autores principales: | Willett, Brian J, McMonagle, Elizabeth L, Logan, Nicola, Samman, Ayman, Hosie, Margaret J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563026/ https://www.ncbi.nlm.nih.gov/pubmed/18721458 http://dx.doi.org/10.1186/1742-4690-5-77 |
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