Models from experiments: combinatorial drug perturbations of cancer cells

We present a novel method for deriving network models from molecular profiles of perturbed cellular systems. The network models aim to predict quantitative outcomes of combinatorial perturbations, such as drug pair treatments or multiple genetic alterations. Mathematically, we represent the system b...

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Detalles Bibliográficos
Autores principales: Nelander, Sven, Wang, Weiqing, Nilsson, Björn, She, Qing-Bai, Pratilas, Christine, Rosen, Neal, Gennemark, Peter, Sander, Chris
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564730/
https://www.ncbi.nlm.nih.gov/pubmed/18766176
http://dx.doi.org/10.1038/msb.2008.53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564730/
https://www.ncbi.nlm.nih.gov/pubmed/18766176
http://dx.doi.org/10.1038/msb.2008.53

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