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Bosentan regulates the expression of adhesion molecules on circulating T cells and serum soluble adhesion molecules in systemic sclerosis-associated pulmonary arterial hypertension

OBJECTIVES: To study the expression of adhesion molecules in patients with systemic sclerosis (SSc) with and without pulmonary arterial hypertension (PAH) and the effects of therapy with the endothelin-1 (ET-1) receptor antagonist, bosentan. METHODS: In all, 35 patients with SSc and 25 healthy donor...

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Detalles Bibliográficos
Autores principales: Iannone, F, Riccardi, M T, Guiducci, S, Bizzoca, R, Cinelli, M, Matucci-Cerinic, M, Lapadula, G
Formato: Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564790/
https://www.ncbi.nlm.nih.gov/pubmed/18029384
http://dx.doi.org/10.1136/ard.2007.080424