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Long-term effects of bosentan on quality of life, survival, safety and tolerability in pulmonary arterial hypertension related to connective tissue diseases

OBJECTIVES: This study investigated the long-term effects of bosentan, an oral endothelin ET(A)/ET(B) receptor antagonist, in patients with pulmonary arterial hypertension (PAH) exclusively related to connective tissue diseases (CTD). METHODS: A total of 53 patients with PAH related to connective ti...

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Detalles Bibliográficos
Autores principales: Denton, C P, Pope, J E, Peter, H-H, Gabrielli, A, Boonstra, A, van den Hoogen, F H J, Riemekasten, G, De Vita, S, Morganti, A, Dölberg, M, Berkani, O, Guillevin, L
Formato: Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564804/
https://www.ncbi.nlm.nih.gov/pubmed/18055477
http://dx.doi.org/10.1136/ard.2007.079921