Cargando…

Long-term effects of bosentan on quality of life, survival, safety and tolerability in pulmonary arterial hypertension related to connective tissue diseases

OBJECTIVES: This study investigated the long-term effects of bosentan, an oral endothelin ET(A)/ET(B) receptor antagonist, in patients with pulmonary arterial hypertension (PAH) exclusively related to connective tissue diseases (CTD). METHODS: A total of 53 patients with PAH related to connective ti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Denton, C P, Pope, J E, Peter, H-H, Gabrielli, A, Boonstra, A, van den Hoogen, F H J, Riemekasten, G, De Vita, S, Morganti, A, Dölberg, M, Berkani, O, Guillevin, L
Formato:	Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2008
Materias:	Extended Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564804/ https://www.ncbi.nlm.nih.gov/pubmed/18055477 http://dx.doi.org/10.1136/ard.2007.079921

Ejemplares similares

Bosentan regulates the expression of adhesion molecules on circulating T cells and serum soluble adhesion molecules in systemic sclerosis-associated pulmonary arterial hypertension
por: Iannone, F, et al.
Publicado: (2008)

Safety and tolerability of bosentan in the management of pulmonary arterial hypertension
por: Roberts, Kari E, et al.
Publicado: (2009)

Enhanced Vasodilator Responses to CGRP (Calcitonin Gene-Related Peptide) in Subcutaneous Arteries in Human Hypertension
por: Lind, H., et al.
Publicado: (2001)

The Role of CGRP in the Development of Morphine Tolerance and Physical Dependence
por: Powell, K. J., et al.
Publicado: (2001)

Gender Differences in the Development of Pulmonary Hypertension (PH)
por: Vijay, Palaniswamy, et al.
Publicado: (2001)

Bosentan monohydrate
por: Kaur, Manpreet, et al.
Publicado: (2012)

Efficacy, safety and tolerability of bosentan as an adjuvant to sildenafil and sildenafil alone in persistant pulmonary hypertension of newborn (PPHN)
por: Vijay Kumar, J.R., et al.
Publicado: (2021)

Adalimumab effectively reduces the signs and symptoms of active ankylosing spondylitis in patients with total spinal ankylosis
por: van der Heijde, D, et al.
Publicado: (2008)

CGRP as a Migraine Inducing Substance
por: Olesen, J., et al.
Publicado: (2001)

Cgrp Release and Synergistic Interactions with Nitric Oxide: Implications for Pathogenesis of Septic Shock and the Vascular Problems of Diabetes Mellitus and Aging
por: Fiscus, R.R., et al.
Publicado: (2001)

Investigating the role of the HLA-Cw*06 and HLA-DRB1 genes in susceptibility to psoriatic arthritis: comparison with psoriasis and undifferentiated inflammatory arthritis
por: Ho, P Y P C, et al.
Publicado: (2008)

The clinical response to infliximab in rheumatoid arthritis is in part dependent on pretreatment tumour necrosis factor α expression in the synovium
por: Wijbrandts, C A, et al.
Publicado: (2008)

Synovial tissue response to rituximab: mechanism of action and identification of biomarkers of response
por: Thurlings, R M, et al.
Publicado: (2008)

Recommendations for the content and conduct of European League Against Rheumatism (EULAR) musculoskeletal ultrasound courses
por: Naredo, E, et al.
Publicado: (2008)

Local and systemic glucocorticoid metabolism in inflammatory arthritis
por: Hardy, R, et al.
Publicado: (2008)

Will you give my kidney back? Organ restitution in living-related kidney transplantation: ethical analyses
por: Nakazawa, Eisuke, et al.
Publicado: (2020)

Review of bosentan in the management of pulmonary arterial hypertension
por: Gabbay, Eli, et al.
Publicado: (2007)

Abatacept inhibits progression of structural damage in rheumatoid arthritis: results from the long-term extension of the AIM trial
por: Genant, H K, et al.
Publicado: (2008)

A Novel Nonpeptide CGRP Receptor Antagonist, ‘Compound 1’ (WO98/11128) Is a High Affinity Competitive Antagonist at the CGRP1 Receptor in Human Coronary Arteries
por: Hasbak, P., et al.
Publicado: (2001)

Septic arthritis in Iceland 1990–2002: increasing incidence due to iatrogenic infections
por: Geirsson, Á J, et al.
Publicado: (2008)

New CGRP Antagonists
por: Doods, H. N., et al.
Publicado: (2001)

CGRP and Adrenomedullin Modulate Synaptic Transmission in Purkinje Cells
por: Cater, H., et al.
Publicado: (2001)

Relative mRNA Quantification of Calcitonin Receptor-Like Receptor (CRLR) and Receptor Activity Modifying Proteins (RAMPs) by Real-Time PCR
por: Eskesen, K., et al.
Publicado: (2001)

Differential expression of syndecans and glypicans in chronically inflamed synovium
por: Patterson, A M, et al.
Publicado: (2008)

Calcitonin Gene-Related Peptide (Cgrp), Adrenomedullin (Am), Amylin, And Calcitonin (Ct) Receptors And Overlapping Biological Actions
por: Fischer, J.A., et al.
Publicado: (2001)

Passport to freedom? Immunity passports for COVID-19
por: Brown, Rebecca C H, et al.
Publicado: (2020)

Towards a new model of global health justice: the case of COVID-19 vaccines
por: Jecker, Nancy S, et al.
Publicado: (2023)

Efficacy and safety of a novel synergistic drug candidate, CRx-102, in hand osteoarthritis
por: Kvien, T K, et al.
Publicado: (2008)

Pharmacokinetic and Pharmacodynamic Comparison of Sildenafil‐Bosentan and Sildenafil‐Ambrisentan Combination Therapies for Pulmonary Hypertension
por: Hakamata, A, et al.
Publicado: (2016)

Evidence for the Differential Distribution of at Least Two Adrenomedullin Receptor Subtypes in the Rat Brain
por: Chabot, J.-G., et al.
Publicado: (2001)

Structural Determinants in the Calcitonin Receptor-Like Receptor (Crlr) Important for Cgrp and Adrenomedullin (Am) Receptor Function of Crlr/Receptor-Activity-Modifying Protein (Ramp) 1 and Crlr/Ramp2 Heterodimers
por: Born, W., et al.
Publicado: (2001)

Bosentan and sildenafil in the treatment of HIV-associated pulmonary hypertension
por: Chinello, Pierangelo, et al.
Publicado: (2011)

Bosentan for pulmonary hypertension secondary to idiopathic pulmonary fibrosis
por: Onda, Naomi, et al.
Publicado: (2014)

Can we learn from hidden mistakes? Self-fulfilling prophecy and responsible neuroprognostic innovation
por: Mertens, Mayli, et al.
Publicado: (2022)

Altered Neuroadaptation in Opiate Dependence and Neurogenic Inflammatory Nociception in αCGRP Deficient Mice
por: Salmon, A.-M., et al.
Publicado: (2001)

Repeated Salmon Calcitonin Injection Lowers Body Weight and Body Fat
por: Lutz, T. A., et al.
Publicado: (2001)

Altered blood gene expression in the obesity-related type 2 diabetes cluster may be causally involved in lipid metabolism: a Mendelian randomisation study
por: de Klerk, Juliette A., et al.
Publicado: (2023)

Amylin as a Neuroendocrine Hormone
por: Young, Andrew A.
Publicado: (2001)

Distribution of Receptor Activity Modifying Protein (RAMP) mRNAS in the Rat Central Nervous System
por: Oliver, K. R., et al.
Publicado: (2001)

Efficacy and safety of abatacept or infliximab vs placebo in ATTEST: a phase III, multi-centre, randomised, double-blind, placebo-controlled study in patients with rheumatoid arthritis and an inadequate response to methotrexate
por: Schiff, M, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_13ks3tlrstai01ilck9d9f5p37