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Role of viral hemagglutinin glycosylation in anti-influenza activities of recombinant surfactant protein D

BACKGROUND: Surfactant protein D (SP-D) plays an important role in innate defense against influenza A viruses (IAVs) and other pathogens. METHODS: We tested antiviral activities of recombinant human SP-D against a panel of IAV strains that vary in glycosylation sites on their hemagglutinin (HA). For...

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Detalles Bibliográficos
Autores principales: Hartshorn, Kevan L, Webby, Richard, White, Mitchell R, Tecle, Tesfaldet, Pan, Clark, Boucher, Susan, Moreland, Rodney J, Crouch, Erika C, Scheule, Ronald K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564921/
https://www.ncbi.nlm.nih.gov/pubmed/18811961
http://dx.doi.org/10.1186/1465-9921-9-65