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Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres

BACKGROUND: MicroRNAs (miRNAs), some of which function as oncogenes or tumor suppressor genes, are involved in carcinogenesis via regulating cell proliferation and/or cell death. MicroRNA miR-34 was recently found to be a direct target of p53, functioning downstream of the p53 pathway as a tumor sup...

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Detalles Bibliográficos
Autores principales: Ji, Qing, Hao, Xinbao, Meng, Yang, Zhang, Min, DeSano, Jeffrey, Fan, Daiming, Xu, Liang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564978/
https://www.ncbi.nlm.nih.gov/pubmed/18803879
http://dx.doi.org/10.1186/1471-2407-8-266