HLA-Driven Convergence of HIV-1 Viral Subtypes B and F Toward the Adaptation to Immune Responses in Human Populations

BACKGROUND: Cytotoxic T-Lymphocyte (CTL) response drives the evolution of HIV-1 at a host-level by selecting HLA-restricted escape mutations. Dissecting the dynamics of these escape mutations at a population-level would help to understand how HLA-mediated selection drives the evolution of HIV-1. MET...

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Detalles Bibliográficos
Autores principales: Dilernia, Dario Alberto, Jones, Leandro, Rodriguez, Sabrina, Turk, Gabriela, Rubio, Andrea E., Pampuro, Sandra, Gomez-Carrillo, Manuel, Bautista, Christian, Deluchi, Gabriel, Benetucci, Jorge, Lasala, María Beatriz, Lourtau, Leonardo, Losso, Marcelo Horacio, Perez, Héctor, Cahn, Pedro, Salomón, Horacio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565011/
https://www.ncbi.nlm.nih.gov/pubmed/18941505
http://dx.doi.org/10.1371/journal.pone.0003429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565011/
https://www.ncbi.nlm.nih.gov/pubmed/18941505
http://dx.doi.org/10.1371/journal.pone.0003429

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