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A Distinct Translation Initiation Mechanism Generates Cryptic Peptides for Immune Surveillance

MHC class I molecules present a comprehensive mixture of peptides on the cell surface for immune surveillance. The peptides represent the intracellular protein milieu produced by translation of endogenous mRNAs. Unexpectedly, the peptides are encoded not only in conventional AUG initiated translatio...

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Detalles Bibliográficos
Autores principales: Starck, Shelley R., Ow, Yongkai, Jiang, Vivian, Tokuyama, Maria, Rivera, Mark, Qi, Xin, Roberts, Richard W., Shastri, Nilabh
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565129/
https://www.ncbi.nlm.nih.gov/pubmed/18941630
http://dx.doi.org/10.1371/journal.pone.0003460