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Oseltamivir Is Adequately Absorbed Following Nasogastric Administration to Adult Patients with Severe H5N1 Influenza

In the absence of a parenteral drug, oral oseltamivir is currently recommended by the WHO for treating H5N1 influenza. Whether oseltamivir absorption is adequate in severe influenza is unknown. We measured the steady state, plasma concentrations of nasogastrically administered oseltamivir 150 mg bid...

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Detalles Bibliográficos
Autores principales: Taylor, Walter R. J., Thinh, Bui Nghia, Anh, Giang Thuc, Horby, Peter, Wertheim, Heiman, Lindegardh, Niklas, de Jong, Menno D., Stepniewska, Kasia, Hanh, Tran Thuy, Hien, Nguyen Duc, Bien, Ngo Minh, Chau, Ngo Quy, Fox, Annette, Ngoc, Nghiem My, Crusat, Martin, Farrar, Jeremy J., White, Nicholas J., Ha, Nguyen Hong, Lien, Trinh Thi, Trung, Nguyen Vu, Day, Nicholas, Binh, Nguyen Gia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565445/
https://www.ncbi.nlm.nih.gov/pubmed/18923671
http://dx.doi.org/10.1371/journal.pone.0003410