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The Role of Insulin, Insulin Growth Factor, and Insulin-Degrading Enzyme in Brain Aging and Alzheimer's Disease
Most brain insulin comes from the pancreas and is taken up by the brain by what appears to be a receptor-based carrier. Type 2 diabetes animal models associated with insulin resistance show reduced insulin brain uptake and content. Recent data point to changes in the insulin receptor cascade in obes...
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565470/ https://www.ncbi.nlm.nih.gov/pubmed/16444902 http://dx.doi.org/10.1155/NP.2005.311 |