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The Anticonvulsant Ethosuximide Disrupts Sensory Function to Extend C. elegans Lifespan

Ethosuximide is a medication used to treat seizure disorders in humans, and we previously demonstrated that ethosuximide can delay age-related changes and extend the lifespan of the nematode Caenorhabditis elegans. The mechanism of action of ethosuximide in lifespan extension is unknown, and elucida...

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Detalles Bibliográficos
Autores principales: Collins, James J., Evason, Kimberley, Pickett, Christopher L., Schneider, Daniel L., Kornfeld, Kerry
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565500/
https://www.ncbi.nlm.nih.gov/pubmed/18949032
http://dx.doi.org/10.1371/journal.pgen.1000230