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Genome-Wide Analysis of Human Disease Alleles Reveals That Their Locations Are Correlated in Paralogous Proteins

The millions of mutations and polymorphisms that occur in human populations are potential predictors of disease, of our reactions to drugs, of predisposition to microbial infections, and of age-related conditions such as impaired brain and cardiovascular functions. However, predicting the phenotypic...

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Detalles Bibliográficos
Autores principales: Yandell, Mark, Moore, Barry, Salas, Fidel, Mungall, Chris, MacBride, Andrew, White, Charles, Reese, Martin G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565504/
https://www.ncbi.nlm.nih.gov/pubmed/18989397
http://dx.doi.org/10.1371/journal.pcbi.1000218