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Molecular and macromolecular alterations of recombinant adenoviral vectors do not resolve changes in hepatic drug metabolism during infection

In this report we test the hypothesis that long-term virus-induced alterations in CYP occur from changes initiated by the virus that may not be related to the immune response. Enzyme activity, protein expression and mRNA of CYP3A2, a correlate of human CYP3A4, and CYP2C11, responsive to inflammatory...

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Detalles Bibliográficos
Autores principales: Callahan, Shellie M, Wonganan, Piyanuch, Croyle, Maria A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565663/
https://www.ncbi.nlm.nih.gov/pubmed/18826641
http://dx.doi.org/10.1186/1743-422X-5-111