Unusual histological presentation in neurofibromas: Two case reports
Various histological variants of neurofibroma have been described. The objective of this paper is to discuss the unusual histological findings seen in two cases of neurofibromas associated with neurofibromatosis type 1 Both cases presented with multiple subcutaneous nodules. Surgical excision of the...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565668/ https://www.ncbi.nlm.nih.gov/pubmed/18823533 http://dx.doi.org/10.1186/1757-1626-1-188 |
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author | Joshi, Deepti Gangane, Nitin Kishore, Sanjeev Vagha, Sunita |
author_facet | Joshi, Deepti Gangane, Nitin Kishore, Sanjeev Vagha, Sunita |
author_sort | Joshi, Deepti |
collection | PubMed |
description | Various histological variants of neurofibroma have been described. The objective of this paper is to discuss the unusual histological findings seen in two cases of neurofibromas associated with neurofibromatosis type 1 Both cases presented with multiple subcutaneous nodules. Surgical excision of the largest nodule was done in both the cases. Histological examination of case no.1 revealed a benign tumor of the peripheral nerve sheath, of neurofibroma type with presence of mucus producing glands. The epithelial component was benign in this case. The second case showed presence of rosettes in between areas of typical neurofibroma. |
format | Text |
id | pubmed-2565668 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-25656682008-10-10 Unusual histological presentation in neurofibromas: Two case reports Joshi, Deepti Gangane, Nitin Kishore, Sanjeev Vagha, Sunita Cases J Case Report Various histological variants of neurofibroma have been described. The objective of this paper is to discuss the unusual histological findings seen in two cases of neurofibromas associated with neurofibromatosis type 1 Both cases presented with multiple subcutaneous nodules. Surgical excision of the largest nodule was done in both the cases. Histological examination of case no.1 revealed a benign tumor of the peripheral nerve sheath, of neurofibroma type with presence of mucus producing glands. The epithelial component was benign in this case. The second case showed presence of rosettes in between areas of typical neurofibroma. BioMed Central 2008-09-29 /pmc/articles/PMC2565668/ /pubmed/18823533 http://dx.doi.org/10.1186/1757-1626-1-188 Text en Copyright © 2008 Joshi et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Joshi, Deepti Gangane, Nitin Kishore, Sanjeev Vagha, Sunita Unusual histological presentation in neurofibromas: Two case reports |
title | Unusual histological presentation in neurofibromas: Two case reports |
title_full | Unusual histological presentation in neurofibromas: Two case reports |
title_fullStr | Unusual histological presentation in neurofibromas: Two case reports |
title_full_unstemmed | Unusual histological presentation in neurofibromas: Two case reports |
title_short | Unusual histological presentation in neurofibromas: Two case reports |
title_sort | unusual histological presentation in neurofibromas: two case reports |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565668/ https://www.ncbi.nlm.nih.gov/pubmed/18823533 http://dx.doi.org/10.1186/1757-1626-1-188 |
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