Unusual histological presentation in neurofibromas: Two case reports

Various histological variants of neurofibroma have been described. The objective of this paper is to discuss the unusual histological findings seen in two cases of neurofibromas associated with neurofibromatosis type 1 Both cases presented with multiple subcutaneous nodules. Surgical excision of the...

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Autores principales: Joshi, Deepti, Gangane, Nitin, Kishore, Sanjeev, Vagha, Sunita
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565668/
https://www.ncbi.nlm.nih.gov/pubmed/18823533
http://dx.doi.org/10.1186/1757-1626-1-188
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author Joshi, Deepti
Gangane, Nitin
Kishore, Sanjeev
Vagha, Sunita
author_facet Joshi, Deepti
Gangane, Nitin
Kishore, Sanjeev
Vagha, Sunita
author_sort Joshi, Deepti
collection PubMed
description Various histological variants of neurofibroma have been described. The objective of this paper is to discuss the unusual histological findings seen in two cases of neurofibromas associated with neurofibromatosis type 1 Both cases presented with multiple subcutaneous nodules. Surgical excision of the largest nodule was done in both the cases. Histological examination of case no.1 revealed a benign tumor of the peripheral nerve sheath, of neurofibroma type with presence of mucus producing glands. The epithelial component was benign in this case. The second case showed presence of rosettes in between areas of typical neurofibroma.
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spelling pubmed-25656682008-10-10 Unusual histological presentation in neurofibromas: Two case reports Joshi, Deepti Gangane, Nitin Kishore, Sanjeev Vagha, Sunita Cases J Case Report Various histological variants of neurofibroma have been described. The objective of this paper is to discuss the unusual histological findings seen in two cases of neurofibromas associated with neurofibromatosis type 1 Both cases presented with multiple subcutaneous nodules. Surgical excision of the largest nodule was done in both the cases. Histological examination of case no.1 revealed a benign tumor of the peripheral nerve sheath, of neurofibroma type with presence of mucus producing glands. The epithelial component was benign in this case. The second case showed presence of rosettes in between areas of typical neurofibroma. BioMed Central 2008-09-29 /pmc/articles/PMC2565668/ /pubmed/18823533 http://dx.doi.org/10.1186/1757-1626-1-188 Text en Copyright © 2008 Joshi et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Joshi, Deepti
Gangane, Nitin
Kishore, Sanjeev
Vagha, Sunita
Unusual histological presentation in neurofibromas: Two case reports
title Unusual histological presentation in neurofibromas: Two case reports
title_full Unusual histological presentation in neurofibromas: Two case reports
title_fullStr Unusual histological presentation in neurofibromas: Two case reports
title_full_unstemmed Unusual histological presentation in neurofibromas: Two case reports
title_short Unusual histological presentation in neurofibromas: Two case reports
title_sort unusual histological presentation in neurofibromas: two case reports
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565668/
https://www.ncbi.nlm.nih.gov/pubmed/18823533
http://dx.doi.org/10.1186/1757-1626-1-188
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