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Computational detection of significant variation in binding affinity across two sets of sequences with application to the analysis of replication origins in yeast

BACKGROUND: In analyzing the stability of DNA replication origins in Saccharomyces cerevisiae we faced the question whether one set of sequences is significantly enriched in the number and/or the quality of the matches of a particular position weight matrix relative to another set. RESULTS: We prese...

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Detalles Bibliográficos
Autores principales: Keich, Uri, Gao, Hong, Garretson, Jeffrey S, Bhaskar, Anand, Liachko, Ivan, Donato, Justin, Tye, Bik K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566582/
https://www.ncbi.nlm.nih.gov/pubmed/18786274
http://dx.doi.org/10.1186/1471-2105-9-372