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Computational detection of significant variation in binding affinity across two sets of sequences with application to the analysis of replication origins in yeast
BACKGROUND: In analyzing the stability of DNA replication origins in Saccharomyces cerevisiae we faced the question whether one set of sequences is significantly enriched in the number and/or the quality of the matches of a particular position weight matrix relative to another set. RESULTS: We prese...
Autores principales: | Keich, Uri, Gao, Hong, Garretson, Jeffrey S, Bhaskar, Anand, Liachko, Ivan, Donato, Justin, Tye, Bik K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566582/ https://www.ncbi.nlm.nih.gov/pubmed/18786274 http://dx.doi.org/10.1186/1471-2105-9-372 |
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