Fluorescence Resonance Energy Transfer Imaging Reveals that Chemokine-Binding Modulates Heterodimers of CXCR4 and CCR5 Receptors

BACKGROUND: Dimerization has emerged as an important feature of chemokine G-protein-coupled receptors. CXCR4 and CCR5 regulate leukocyte chemotaxis and also serve as a co-receptor for HIV entry. Both receptors are recruited to the immunological synapse during T-cell activation. However, it is not cl...

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Detalles Bibliográficos
Autores principales: Isik, Nilgun, Hereld, Dale, Jin, Tian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566588/
https://www.ncbi.nlm.nih.gov/pubmed/18923649
http://dx.doi.org/10.1371/journal.pone.0003424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566588/
https://www.ncbi.nlm.nih.gov/pubmed/18923649
http://dx.doi.org/10.1371/journal.pone.0003424

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