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Human Keratinocytes Are Vanilloid Resistant

BACKGROUND: Use of capsaicin or resiniferatoxin (RTX) as analgesics is an attractive therapeutic option. RTX opens the cation channel inflammatory pain/vanilloid receptor type 1 (TRPV1) permanently and selectively removes nociceptive neurons by Ca(2+)-cytotoxicity. Paradoxically, not only nociceptor...

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Detalles Bibliográficos
Autores principales: Pecze, László, Szabó, Kornélia, Széll, Márta, Jósvay, Katalin, Kaszás, Krisztián, Kúsz, Erzsébet, Letoha, Tamás, Prorok, János, Koncz, István, Tóth, András, Kemény, Lajos, Vizler, Csaba, Oláh, Zoltán
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566593/
https://www.ncbi.nlm.nih.gov/pubmed/18852901
http://dx.doi.org/10.1371/journal.pone.0003419