Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn's Disease Associated ATG16L1 Variant

The genetic risk factors predisposing individuals to the development of inflammatory bowel disease are beginning to be deciphered by genome-wide association studies. Surprisingly, these new data point towards a critical role of autophagy in the pathogenesis of Crohn's disease. A single common c...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuballa, Petric, Huett, Alan, Rioux, John D., Daly, Mark J., Xavier, Ramnik J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566595/
https://www.ncbi.nlm.nih.gov/pubmed/18852889
http://dx.doi.org/10.1371/journal.pone.0003391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566595/
https://www.ncbi.nlm.nih.gov/pubmed/18852889
http://dx.doi.org/10.1371/journal.pone.0003391

Ejemplares similares