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Biological Function and Molecular Mapping of M Antigen in Yeast Phase of Histoplasma capsulatum

Histoplasmosis, due to the intracellular fungus Histoplasma capsulatum, can be diagnosed by demonstrating the presence of antibodies specific to the immunodominant M antigen. However, the role of this protein in the pathogenesis of histoplasmosis has not been elucidated. We sought to structurally an...

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Detalles Bibliográficos
Autores principales: Guimarães, Allan Jefferson, Hamilton, Andrew John, de M. Guedes, Herbert Leonel, Nosanchuk, Joshua Daniel, Zancopé-Oliveira, Rosely Maria
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566600/
https://www.ncbi.nlm.nih.gov/pubmed/18927619
http://dx.doi.org/10.1371/journal.pone.0003449