Computing Power and Sample Size for Case-Control Association Studies with Copy Number Polymorphism: Application of Mixture-Based Likelihood Ratio Test

Recent studies suggest that copy number polymorphisms (CNPs) may play an important role in disease susceptibility and onset. Currently, the detection of CNPs mainly depends on microarray technology. For case-control studies, conventionally, subjects are assigned to a specific CNP category based on t...

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Detalles Bibliográficos
Autores principales: Kim, Wonkuk, Gordon, Derek, Sebat, Jonathan, Ye, Kenny Q., Finch, Stephen J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566806/
https://www.ncbi.nlm.nih.gov/pubmed/18941524
http://dx.doi.org/10.1371/journal.pone.0003475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566806/
https://www.ncbi.nlm.nih.gov/pubmed/18941524
http://dx.doi.org/10.1371/journal.pone.0003475

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