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Induction of IgG3 to LPS via Toll-Like Receptor 4 Co-Stimulation

B-cells integrate antigen-specific signals transduced via the B-cell receptor (BCR) and antigen non-specific co-stimulatory signals provided by cytokines and CD40 ligation in order to produce IgG antibodies. Toll-like receptors (TLRs) also provide co-stimulation, but the requirement for TLRs to gene...

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Detalles Bibliográficos
Autores principales: Quintana, Francisco J., Solomon, Aderet, Cohen, Irun R., Nussbaum, Gabriel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566810/
https://www.ncbi.nlm.nih.gov/pubmed/18946502
http://dx.doi.org/10.1371/journal.pone.0003509