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Induction of IgG3 to LPS via Toll-Like Receptor 4 Co-Stimulation
B-cells integrate antigen-specific signals transduced via the B-cell receptor (BCR) and antigen non-specific co-stimulatory signals provided by cytokines and CD40 ligation in order to produce IgG antibodies. Toll-like receptors (TLRs) also provide co-stimulation, but the requirement for TLRs to gene...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566810/ https://www.ncbi.nlm.nih.gov/pubmed/18946502 http://dx.doi.org/10.1371/journal.pone.0003509 |