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A Computational Model for Understanding Stem Cell, Trophectoderm and Endoderm Lineage Determination
BACKGROUND: Recent studies have associated the transcription factors, Oct4, Sox2 and Nanog as parts of a self-regulating network which is responsible for maintaining embryonic stem cell properties: self renewal and pluripotency. In addition, mutual antagonism between two of these and other master re...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566811/ https://www.ncbi.nlm.nih.gov/pubmed/18941526 http://dx.doi.org/10.1371/journal.pone.0003478 |