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The Long March: A Sample Preparation Technique that Enhances Contig Length and Coverage by High-Throughput Short-Read Sequencing

High-throughput short-read technologies have revolutionized DNA sequencing by drastically reducing the cost per base of sequencing information. Despite producing gigabases of sequence per run, these technologies still present obstacles in resequencing and de novo assembly applications due to biased...

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Detalles Bibliográficos
Autores principales: Sorber, Katherine, Chiu, Charles, Webster, Dale, Dimon, Michelle, Ruby, J. Graham, Hekele, Armin, DeRisi, Joseph L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566813/
https://www.ncbi.nlm.nih.gov/pubmed/18941527
http://dx.doi.org/10.1371/journal.pone.0003495