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The Long March: A Sample Preparation Technique that Enhances Contig Length and Coverage by High-Throughput Short-Read Sequencing
High-throughput short-read technologies have revolutionized DNA sequencing by drastically reducing the cost per base of sequencing information. Despite producing gigabases of sequence per run, these technologies still present obstacles in resequencing and de novo assembly applications due to biased...
Autores principales: | Sorber, Katherine, Chiu, Charles, Webster, Dale, Dimon, Michelle, Ruby, J. Graham, Hekele, Armin, DeRisi, Joseph L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566813/ https://www.ncbi.nlm.nih.gov/pubmed/18941527 http://dx.doi.org/10.1371/journal.pone.0003495 |
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