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PhoP: A Missing Piece in the Intricate Puzzle of Mycobacterium tuberculosis Virulence
Inactivation of the transcriptional regulator PhoP results in Mycobacterium tuberculosis attenuation. Preclinical testing has shown that attenuated M. tuberculosis phoP mutants hold promise as safe and effective live vaccine candidates. We focused this study to decipher the virulence networks regula...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566814/ https://www.ncbi.nlm.nih.gov/pubmed/18946503 http://dx.doi.org/10.1371/journal.pone.0003496 |