Cargando…

PhoP: A Missing Piece in the Intricate Puzzle of Mycobacterium tuberculosis Virulence

Inactivation of the transcriptional regulator PhoP results in Mycobacterium tuberculosis attenuation. Preclinical testing has shown that attenuated M. tuberculosis phoP mutants hold promise as safe and effective live vaccine candidates. We focused this study to decipher the virulence networks regula...

Descripción completa

Detalles Bibliográficos
Autores principales: Gonzalo-Asensio, Jesús, Mostowy, Serge, Harders-Westerveen, Jose, Huygen, Kris, Hernández-Pando, Rogelio, Thole, Jelle, Behr, Marcel, Gicquel, Brigitte, Martín, Carlos
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566814/
https://www.ncbi.nlm.nih.gov/pubmed/18946503
http://dx.doi.org/10.1371/journal.pone.0003496