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Identification of a Novel Risk Locus for Multiple Sclerosis at 13q31.3 by a Pooled Genome-Wide Scan of 500,000 Single Nucleotide Polymorphisms

Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous system with an important genetic component and strongest association driven by the HLA genes. We performed a pooling-based genome-wide association study of 500,000 SNPs in order to find new loci associated with...

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Detalles Bibliográficos
Autores principales: Comabella, Manuel, Craig, David W., Camiña-Tato, Montse, Morcillo, Carlos, Lopez, Cristina, Navarro, Arcadi, Rio, Jordi, Montalban, Xavier, Martin, Roland
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566815/
https://www.ncbi.nlm.nih.gov/pubmed/18941528
http://dx.doi.org/10.1371/journal.pone.0003490