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Editing of misaligned 3′-termini by an intrinsic 3′–5′ exonuclease activity residing in the PHP domain of a family X DNA polymerase

Bacillus subtilis gene yshC encodes a family X DNA polymerase (PolX(Bs)), whose biochemical features suggest that it plays a role during DNA repair processes. Here, we show that, in addition to the polymerization activity, PolX(Bs) possesses an intrinsic 3′–5′ exonuclease activity specialized in res...

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Detalles Bibliográficos
Autores principales: Baños, Benito, Lázaro, José M., Villar, Laurentino, Salas, Margarita, de Vega, Miguel
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566882/
https://www.ncbi.nlm.nih.gov/pubmed/18776221
http://dx.doi.org/10.1093/nar/gkn526