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RAG2's non-core domain contributes to the ordered regulation of V(D)J recombination

Variable (diversity) joining [V(D)J] recombination of immune gene loci proceeds in an ordered manner with D to J portions recombining first and then an upstream V joins that recombinant. We present evidence that the non-core domain of recombination activating gene (RAG) protein 2 is involved in the...

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Detalles Bibliográficos
Autores principales: Curry, John D., Schlissel, Mark S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566892/
https://www.ncbi.nlm.nih.gov/pubmed/18776220
http://dx.doi.org/10.1093/nar/gkn553