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Lifetime body mass index and later atherosclerosis risk in young adults: examining causal links using Mendelian randomization in the Cardiovascular Risk in Young Finns study

AIMS: Mendelian randomization uses genetic variants related to environmentally modifiable risk factors in an attempt to improve causal inference from observational data. We examined the effect of lifetime body mass index (BMI) on adult carotid intima-media thickness (CIMT) and various atheroscleroti...

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Detalles Bibliográficos
Autores principales: Kivimäki, Mika, Smith, George Davey, Timpson, Nic J., Lawlor, Debbie A., Batty, G. David, Kähönen, Mika, Juonala, Markus, Rönnemaa, Tapani, Viikari, Jorma S.A., Lehtimäki, Terho, Raitakari, Olli T.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567023/
https://www.ncbi.nlm.nih.gov/pubmed/18550552
http://dx.doi.org/10.1093/eurheartj/ehn252