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TOR Regulates Cell Death Induced by Telomere Dysfunction in Budding Yeast

Telomere dysfunction is known to induce growth arrest (senescence) and cell death. However, the regulation of the senescence-death process is poorly understood. Here using a yeast dysfunctional telomere model cdc13-1, which carries a temperature sensitive-mutant telomere binding protein Cdc13p, we d...

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Detalles Bibliográficos
Autores principales: Qi, Haiyan, Chen, Yongjie, Fu, Xuan, Lin, Chao-Po, Zheng, X. F. Steven, Liu, Leroy F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567032/
https://www.ncbi.nlm.nih.gov/pubmed/18949037
http://dx.doi.org/10.1371/journal.pone.0003520