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Isoforms of endothelin-converting enzyme-1 (ECE-1) have opposing effects on prostate cancer cell invasion

Cross-talk between tumour and stromal cells can profoundly influence cancer cell invasion by increasing the availability of mitogenic peptides such as endothelin-1 (ET-1). Endothelin-1 is elevated in men with metastatic prostate cancer (PC), and can exert both an autocrine (epithelial) and a paracri...

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Detalles Bibliográficos
Autores principales: Lambert, L A, Whyteside, A R, Turner, A J, Usmani, B A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567069/
https://www.ncbi.nlm.nih.gov/pubmed/18781169
http://dx.doi.org/10.1038/sj.bjc.6604631