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Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer
The unique metabolism of most solid tumours (aerobic glycolysis, i.e., Warburg effect) is not only the basis of diagnosing cancer with metabolic imaging but might also be associated with the resistance to apoptosis that characterises cancer. The glycolytic phenotype in cancer appears to be the commo...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567082/ https://www.ncbi.nlm.nih.gov/pubmed/18766181 http://dx.doi.org/10.1038/sj.bjc.6604554 |