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Neoadjuvant continuous infusion of weekly 5-fluorouracil and escalating doses of oxaliplatin plus concurrent radiation in locally advanced oesophageal squamous cell carcinoma: results of a phase I/II trial

Oxaliplatin and 5-fluorouracil have a significant activity in locally advanced oesophageal squamous cell cancer (OSCC). However, their optimal dosage and efficacy when combined with concurrent radiotherapy as neoadjuvant treatment are unknown. This non-randomised, phase I/II study aimed to define th...

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Detalles Bibliográficos
Autores principales: Lorenzen, S, Brücher, B, Zimmermann, F, Geinitz, H, Riera, J, Schuster, T, Roethling, N, Höfler, H, Ott, K, Peschel, C, Siewert, J R, Molls, M, Lordick, F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567089/
https://www.ncbi.nlm.nih.gov/pubmed/18797462
http://dx.doi.org/10.1038/sj.bjc.6604659