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Two Pathways Recruit Telomerase to Saccharomyces cerevisiae Telomeres

The catalytic subunit of yeast telomerase, Est2p, is a telomere associated throughout most of the cell cycle, while the Est1p subunit binds only in late S/G2 phase, the time of telomerase action. Est2p binding in G1/early S phase requires a specific interaction between telomerase RNA (TLC1) and Ku80...

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Detalles Bibliográficos
Autores principales: Chan, Angela, Boulé, Jean-Baptiste, Zakian, Virginia A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567097/
https://www.ncbi.nlm.nih.gov/pubmed/18949040
http://dx.doi.org/10.1371/journal.pgen.1000236