Cargando…

Numt-Mediated Double-Strand Break Repair Mitigates Deletions during Primate Genome Evolution

Non-homologous end joining (NHEJ) is the major mechanism of double-strand break repair (DSBR) in mammalian cells. NHEJ has traditionally been inferred from experimental systems involving induced double strand breaks (DSBs). Whether or not the spectrum of repair events observed in experimental NHEJ r...

Descripción completa

Detalles Bibliográficos
Autores principales: Hazkani-Covo, Einat, Covo, Shay
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567098/
https://www.ncbi.nlm.nih.gov/pubmed/18949041
http://dx.doi.org/10.1371/journal.pgen.1000237