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Numt-Mediated Double-Strand Break Repair Mitigates Deletions during Primate Genome Evolution
Non-homologous end joining (NHEJ) is the major mechanism of double-strand break repair (DSBR) in mammalian cells. NHEJ has traditionally been inferred from experimental systems involving induced double strand breaks (DSBs). Whether or not the spectrum of repair events observed in experimental NHEJ r...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567098/ https://www.ncbi.nlm.nih.gov/pubmed/18949041 http://dx.doi.org/10.1371/journal.pgen.1000237 |