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In vitro generation of cytotoxic and regulatory T cells by fusions of human dendritic cells and hepatocellular carcinoma cells

BACKGROUND: Human hepatocellular carcinoma (HCC) cells express WT1 and/or carcinoembryonic antigen (CEA) as potential targets for the induction of antitumor immunity. In this study, generation of cytotoxic T lymphocytes (CTL) and regulatory T cells (Treg) by fusions of dendritic cells (DCs) and HCC...

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Detalles Bibliográficos
Autores principales: Koido, Shigeo, Homma, Sadamu, Hara, Eiichi, Mitsunaga, Makoto, Namiki, Yoshihisa, Takahara, Akitaka, Nagasaki, Eijiro, Komita, Hideo, Sagawa, Yukiko, Ohkusa, Toshifumi, Fujise, Kiyotaka, Gong, Jianlin, Tajiri, Hisao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567290/
https://www.ncbi.nlm.nih.gov/pubmed/18793383
http://dx.doi.org/10.1186/1479-5876-6-51