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Similarity of aberrant DNA methylation in Barrett's esophagus and esophageal adenocarcinoma
BACKGROUND: Barrett's esophagus (BE) is the metaplastic replacement of squamous with columnar epithelium in the esophagus, as a result of reflux. It is the major risk factor for the development of esophageal adenocarcinoma (EAC). Methylation of CpG dinucleotides of normally unmethylated genes i...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567345/ https://www.ncbi.nlm.nih.gov/pubmed/18831746 http://dx.doi.org/10.1186/1476-4598-7-75 |