Cargando…

Similarity of aberrant DNA methylation in Barrett's esophagus and esophageal adenocarcinoma

BACKGROUND: Barrett's esophagus (BE) is the metaplastic replacement of squamous with columnar epithelium in the esophagus, as a result of reflux. It is the major risk factor for the development of esophageal adenocarcinoma (EAC). Methylation of CpG dinucleotides of normally unmethylated genes i...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Eric, De Young, Neville J, Pavey, Sandra J, Hayward, Nicholas K, Nancarrow, Derek J, Whiteman, David C, Smithers, B Mark, Ruszkiewicz, Andrew R, Clouston, Andrew D, Gotley, David C, Devitt, Peter G, Jamieson, Glyn G, Drew, Paul A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567345/
https://www.ncbi.nlm.nih.gov/pubmed/18831746
http://dx.doi.org/10.1186/1476-4598-7-75