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Reprogramming Primordial Germ Cells into Pluripotent Stem Cells

BACKGROUND: Specification of primordial germ cells (PGCs) results in the conversion of pluripotent epiblast cells into monopotent germ cell lineage. Blimp1/Prmt5 complex plays a critical role in the specification and maintenance of the early germ cell lineage. However, PGCs can be induced to dediffe...

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Detalles Bibliográficos
Autores principales: Durcova-Hills, Gabriela, Tang, Fuchou, Doody, Gina, Tooze, Reuben, Surani, M. Azim
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567847/
https://www.ncbi.nlm.nih.gov/pubmed/18953407
http://dx.doi.org/10.1371/journal.pone.0003531