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Reprogramming Primordial Germ Cells into Pluripotent Stem Cells
BACKGROUND: Specification of primordial germ cells (PGCs) results in the conversion of pluripotent epiblast cells into monopotent germ cell lineage. Blimp1/Prmt5 complex plays a critical role in the specification and maintenance of the early germ cell lineage. However, PGCs can be induced to dediffe...
Autores principales: | Durcova-Hills, Gabriela, Tang, Fuchou, Doody, Gina, Tooze, Reuben, Surani, M. Azim |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567847/ https://www.ncbi.nlm.nih.gov/pubmed/18953407 http://dx.doi.org/10.1371/journal.pone.0003531 |
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