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Human ESCs predisposition to karyotypic instability: Is a matter of culture adaptation or differential vulnerability among hESC lines due to inherent properties?

BACKGROUND: The use of human embryonic stem cells (hESCs) in research is increasing and hESCs hold the promise for many biological, clinical and toxicological studies. Human ESCs are expected to be chromosomally stable since karyotypic changes represent a pitfall for potential future applications. R...

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Detalles Bibliográficos
Autores principales: Catalina, Puri, Montes, Rosa, Ligero, Gertru, Sanchez, Laura, de la Cueva, Teresa, Bueno, Clara, Leone, Paola E, Menendez, Pablo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567976/
https://www.ncbi.nlm.nih.gov/pubmed/18834512
http://dx.doi.org/10.1186/1476-4598-7-76