Strong Signature of Natural Selection within an FHIT Intron Implicated in Prostate Cancer Risk

Previously, a candidate gene linkage approach on brother pairs affected with prostate cancer identified a locus of prostate cancer susceptibility at D3S1234 within the fragile histidine triad gene (FHIT), a tumor suppressor that induces apoptosis. Subsequent association tests on 16 SNPs spanning app...

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Detalles Bibliográficos
Autores principales: Ding, Yan, Larson, Garrett, Rivas, Guillermo, Lundberg, Cathryn, Geller, Louis, Ouyang, Ching, Weitzel, Jeffrey, Archambeau, John, Slater, Jerry, Daly, Mary B., Benson, Al B., Kirkwood, John M., O'Dwyer, Peter J., Sutphen, Rebecca, Stewart, James A., Johnson, David, Nordborg, Magnus, Krontiris, Theodore G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568805/
https://www.ncbi.nlm.nih.gov/pubmed/18953408
http://dx.doi.org/10.1371/journal.pone.0003533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568805/
https://www.ncbi.nlm.nih.gov/pubmed/18953408
http://dx.doi.org/10.1371/journal.pone.0003533

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