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Two Estrogen Response Element Sequences Near the PCNA Gene Are Not Responsible for Its Estrogen-Enhanced Expression in MCF7 Cells

BACKGROUND: The proliferating cell nuclear antigen (PCNA) is an essential component of DNA replication, cell cycle regulation, and epigenetic inheritance. High expression of PCNA is associated with poor prognosis in patients with breast cancer. The 5′-region of the PCNA gene contains two computation...

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Detalles Bibliográficos
Autores principales: Wang, Cheng, Yu, Jie, Kallen, Caleb B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568806/
https://www.ncbi.nlm.nih.gov/pubmed/18949048
http://dx.doi.org/10.1371/journal.pone.0003523