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Implication of the F-Box Protein FBXL21 in Circadian Pacemaker Function in Mammals

In mammals, the circadian clock relies on interlocked feedback loops involving clock genes and their protein products. Post-translational modifications control intracellular trafficking, functionality and degradation of clock proteins and are keys to the functioning of the clock as recently exemplif...

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Detalles Bibliográficos
Autores principales: Dardente, Hugues, Mendoza, Jorge, Fustin, Jean-Michel, Challet, Etienne, Hazlerigg, David G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568807/
https://www.ncbi.nlm.nih.gov/pubmed/18953409
http://dx.doi.org/10.1371/journal.pone.0003530